Chitin and Chitosan as Multipurpose Natural Polymers for Groundwater Arsenic Removal and As2O3 Delivery in Tumor Therapy

نویسندگان

  • Letizia Da Sacco
  • Andrea Masotti
چکیده

Chitin and chitosan are natural polysaccharide polymers. These polymers have been used in several agricultural, food protection and nutraceutical applications. Moreover, chitin and chitosan have been also used in biomedical and biotechnological applications as drug delivery systems or in pharmaceutical formulations. So far, there are only few studies dealing with arsenic (As) removal from groundwater using chitin or chitosan and no evidence of the use of these natural polymers for arsenic trioxide (As(2)O(3)) delivery in tumor therapy. Here we suggest that chitin and/or chitosan might have the right properties to be employed as efficient polymers for such applications. Besides, nanotechnology offers suitable tools for the fabrication of novel nanostructured materials of natural origin. Since different nanostructured materials have already been employed successfully in various multidisciplinary fields, we expect that the integration of nanotechnology and natural polymer chemistry will further lead to innovative applications for environment and medicine.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The antimicrobial of chitin and chitosan extracted from shrimp shell (Palameon elegans)

Palaemon elegans are distributed over a wide coastline of ocean and sea waters. distilled form (chitosan) is a natural polymer with antimicrobial properties that is naturally present in the exoskeleton of crustaceans, including shrimp. Chitin and chitosan are widely used in the pharmaceutical, cosmetic, agricultural, biomedical, food preparation and storage industries. 977 pieces of P. elegans ...

متن کامل

Preparation and evaluation of iron-chitosan composites for removal of As(III) and As(V) from arsenic contaminated real life groundwater.

A study on the removal of arsenic from real life groundwater using iron-chitosan composites is presented. Removal of arsenic(III) and arsenic(V) was studied through adsorption at pH 7.0 under equilibrium and dynamic conditions. The equilibrium data were fitted to Langmuir adsorption models and the various model parameters were evaluated. The monolayer adsorption capacity from the Langmuir model...

متن کامل

Functional Characterization of Chitin and Chitosan

Chitin and its deacetylated derivative chitosan are natural polymers composed of randomly distributed -(1-4)linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine (acetylated unit). Chitin is insoluble in aqueous media while chitosan is soluble in acidic conditions due to the free protonable amino groups present in the D-glucosamine units. Due to their natural origin, both chitin a...

متن کامل

تعیین درجه داستیلاسیون کیتوسان تهیه شده از پوست میگو

Background and purpose: Çhitin, a natural polysaccharide, which is widely existed in the Ârthropod shell such as crab, clobster, shrimp and fungi. Çhitin and its derivative chitosan, a mucopolysaccharide like glycoaminoglycan have been reported to be useful for biomedical applications like wound healing and dressings, drug delivery agents, anti- cholesterolemic agents, blood anticoagulants, a...

متن کامل

Chitosan Microspheres in Novel Drug Delivery Systems

The main aim in the drug therapy of any disease is to attain the desired therapeutic concentration of the drug in plasma or at the site of action and maintain it for the entire duration of treatment. A drug on being used in conventional dosage forms leads to unavoidable fluctuations in the drug concentration leading to under medication or overmedication and increased frequency of dose administr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2010